K-Ras Antibody PA5-44339 from Thermo Fisher Scientific

Product Specs
ItemK-Ras Antibody
CompanyThermo Fisher Scientific
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberPA5-44339
Quantity100 µL
ApplicationsWestern Blot
Concentration0.5 mg/mL
Conjugate/TagUnconjugated
FormatPBS with 2% sucrose and 0.09% sodium azide
ReactivityHuman, Mouse
TargetK-Ras
IsotypeIgG
HostRabbit
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
ImmunogenSynthetic peptide directed towards the N-terminal of human KRAS
NCBI Full Gene NameKirsten rat sarcoma viral oncogene homolog, KRAS proto-oncogene, GTPase
NCBI Gene AliasesKras2, ras, 'C-K-RAS, K-ras, c-Ki-ras, KI-RAS, K-Ras 2, C-K-RAS, NS, K-Ras, p21B, Ki-ras, K-RAS4A, K-RAS4B, RASK2, K-RAS2B, K-RAS2A, c-K-ras, NS3, Kras-2, KRAS1, KRAS2, OES, CFC2, RALD, c-Ki-ras2
ClonalityPolyclonal
PurityAffinity Chromatography
Antibody TypePrimary
Storage-20° C, Avoid Freeze/Thaw Cycles

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Thermo Fisher Scientific

81 Wyman Street

Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

Company Profile

Website: www.thermofisher.com

(1) GZ17-6.02 initiates DNA damage causing autophagosome-dependent HDAC degradation resulting in enhanced anti-PD1 checkpoint inhibitory antibody efficacyJournal of cellular physiologyNovember 1, 2020Booth L, Roberts JL, West C, Von Hoff D, Dent P.

(2) GZ17-6.02 and Doxorubicin Interact to Kill Sarcoma Cells via Autophagy and Death Receptor SignalingFrontiers in oncologyJanuary 1, 2020Booth L, West C, Hoff DV, Dent P.Biologicals. Antibodies directed against RAS proteins: Thermo-Fisher (Waltham MA) N-RAS PA5-14833; K-RAS PA5-44339. Control studies are presented showing on-target specificity of antibodies to detect total protein levels

(3) Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cellsOncogeneJuly 1, 2019Dent P, Booth L, Roberts JL, Liu J, Poklepovic A, Lalani AS, Tuveson D, Martinez J, Hancock JF.Figure 12). Antibodies directed against RAS proteins: Thermo-Fisher (Waltham MA) N-RAS PA5–14833; K-RAS PA5–44339. Based on data from Waters et al, we used two validated siRNA tools to knock down K-RAS or N-RAS for

(4) The Lethality of [Pazopanib + HDAC Inhibitors] Is Enhanced by NeratinibFrontiers in oncologyJanuary 1, 2019Booth L, Roberts JL, Poklepovic A, Dent P.S36A, 211%. Antibodies directed against RAS proteins: Thermo-Fisher (Waltham MA) N-RAS PA5-14833; K-RAS PA5-44339. We used two validated siRNA tools to knock down K-RAS or N-RAS for antibody validation purposes; custom

(5) Afatinib restrains K-RAS-driven lung tumorigenesisScience translational medicineJune 20, 2018Moll HP, Pranz K, Musteanu M, Grabner B, Hruschka N, Mohrherr J, Aigner P, Stiedl P, Brcic L, Laszlo V, et al.and antibodies specifically against G12D mutated K-RAS (Cell Signaling #14429), K-RAS (Invitrogen, PA544339), H-RAS (Santa Cruz, sc34) and N-RAS (Santa Cruz, sc31). Statistical Analysis Graph Pad Prism 5.0

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K-Ras Antibody from Thermo Fisher Scientific

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K-Ras Antibody from Thermo Fisher Scientific

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